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Insights into Microbial Pathogenesis and Immunology from Cryptococcus Neoformans
 
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Insights into Microbial Pathogenesis and Immunology from Cryptococcus Neoformans Air date: Wednesday, January 28, 2015, 3:00:00 PM Category: WALS - Wednesday Afternoon Lectures Runtime: 00:59:37 Description: Wednesday Afternoon Lecture Series The majority of human pathogenic fungi are soil-dwelling microbes that have no obvious need for animal hosts. This raises a fundamental question in microbial pathogenesis: Why do some of these organisms cause disease in mammals? In this lecture we will dissect the biology of the human pathogenic fungus Cryptococcus neoformans in an effort to glean an explanation for the origin of virulence. C. neoformans is an intracellular pathogen with a remarkable replicative strategy that includes the capacity for exciting the host cell without triggering its lysis. This process involves inflicting just enough damage to the host cell to interfere with its microbicidal properties without triggering cell-death pathways such that intracellular replication can proceed unhindered while the host cell remains alive to participate in the exit of fungal cells. The similarity in the interactions between cryptococcal cells with macrophages and amoeba has led to the proposal that the cells' capacity for mammalian virulence emerged accidentally as a result of environmental interactions with phagocytic predators. In this lecture we will also explore the fascinating properties of melanin, an enigmatic pigment that performs a myriad of functions from enhancing cell-wall integrity to energy transduction. We will also consider some of the immunological lessons from studying C. neoformans, which produced important insights into novel antibody protective functions. Finally, we will look at the big picture of fungal pathogenesis and explore the concept of accidental virulence and the likelihood that global warming will bring new fungal diseases. Author: Arturo Casadevall, M.D., Ph.D., Professor in the Department of Medicine and in the Department of Microbiology and Immunology, Albert Einstein College of Medicine; Chair, Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health Permanent link: http://videocast.nih.gov/launch.asp?18822
Views: 3824 nihvcast
Medical Video Lecture: cryptococcus neoformans,MICROBIOLOGY
 
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Views: 4589 allornonelaw
C. neoformans
 
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-- Created using PowToon -- Free sign up at http://www.powtoon.com/youtube/ -- Create animated videos and animated presentations for free. PowToon is a free tool that allows you to develop cool animated clips and animated presentations for your website, office meeting, sales pitch, nonprofit fundraiser, product launch, video resume, or anything else you could use an animated explainer video. PowToon's animation templates help you create animated presentations and animated explainer videos from scratch. Anyone can produce awesome animations quickly with PowToon, without the cost or hassle other professional animation services require.
Views: 1257 Duy Nguyen
Cryptococcus Gattii - Joe Halliday, DO
 
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Dr. Joseph Halliday discusses an emerging fungal pathogen, C. gattii and the recent outbreaks in the Northwest US and British Columbia. C. gattii is an encapsulated yeast most often seen in immunocompromised patients, but epidemic varieties infect immunocompetent patients as well. He also discusses the presence of endemic C. gattii, clinical manifestations of this fungal infection, diagnosis, management, and complications. IDPodcasts brings you essential updates in medical infectious diseases learning, brought to you from the University of South Florida’s Division of Infectious Disease. Stay in touch! Download our app on the Itunes store or find us below: Subscribe to our Youtube Channel: https://www.youtube.com/user/IDPodcasts Visit us on our webpage: http://www.idpodcasts.net/USF_ID_Podcasts/Main/Main.html Follow us on Facebook: https://www.facebook.com/ID-Podcasts-216965201680987/ Tweet to us: https://twitter.com/idpodcasts
Views: 916 IDPodcasts
How Mushrooms Changed the World
 
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David Hibbett, Professor of Biology, Clark University 2017–2018 Fellow, Radcliffe Institute for Advanced Study, Harvard University Fungi receive little attention in mainstream media, but these organisms have an enormous impact on ecosystems and on the production of food and pharmaceuticals. As decomposers, fungi recycle nutrients and are key contributors to the global carbon cycle. David Hibbett will examine the diversity of fungal decay mechanisms and how they have evolved across geologic time. He will also address the controversial hypothesis that fungal evolution contributed to the decline in coal formation at the end of the Carboniferous Period. Public lecture delivered March 27, 2018 for Harvard Museum of Natural History, one of the Harvard Museums of Science & Culture, as part of the Evolution Matters Lecture Series. Series supported by a generous gift from Drs. Herman and Joan Suit.
C. neoformans
 
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-- Created using PowToon -- Free sign up at http://www.powtoon.com/youtube/ -- Create animated videos and animated presentations for free. PowToon is a free tool that allows you to develop cool animated clips and animated presentations for your website, office meeting, sales pitch, nonprofit fundraiser, product launch, video resume, or anything else you could use an animated explainer video. PowToon's animation templates help you create animated presentations and animated explainer videos from scratch. Anyone can produce awesome animations quickly with PowToon, without the cost or hassle other professional animation services require.
Views: 101 thania dominguez
Nocardiosis
 
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Nocardiosis is an infectious disease affecting either the lungs or the whole body. It is due to infection by bacterium of the genus Nocardia, most commonly Nocardia asteroides or Nocardia brasiliensis. It is most common in men, especially those with a weakened immune system. In patients with brain infection, mortality exceeds 80%; in other forms, mortality is 50%, even with appropriate therapy. This video is targeted to blind users. Attribution: Article text available under CC-BY-SA Creative Commons image source in video
Views: 2137 Audiopedia
Histoplasmosis
 
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Views: 60 vaalens
Coccidioidomycosis (CM) - Medical Meaning
 
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https://word2speech.com/medical/ Coccidioidomycosis (CM) Coccidioidomycosis (CM): A disease due to a fungus called Coccidioides immitis. About 40% of people infected with this fungus develop symptoms. Most often they have an influenza-like illness with fever, cough, headaches, rash, and myalgias (muscle pains). Of those people with symptoms, 8% have severe lung disease requiring hospitalization and 7% develop disseminated infection (throughout the body). Groups at high risk from the fungus include African-Americans and Asians, pregnant women in the third trimester, smokers, the elderly, diabetics and people with an impaired immune system. Severe disease tends particularly to strike in HIV-infected persons. The mortality is high in HIV-infected persons with diffuse lung disease. CM meningitis can lead to permanent brain damage. The fungus is in the soil in semiarid areas (primarily in the lower Sonoran life zone). The disease is endemic (constantly present) in the southwestern US and parts of Mexico and South America. Inhalation of airborne spores after disturbance of soil by people or natural disasters (such as wind storms and earthquakes) exposes people (as for example, construction or agricultural workers and archeologists) to the dust containing the spores. A mask helps but does not provide complete protection against the fungus. The incidence of the disease was 15/100,000 in Arizona in 1995. Of persons living in areas with endemic disease, between 10% and 50% have been found to show a positive skin test to CM. In one outbreak, 35 church members from Pennsylvania traveled to Hermosillo, Mexico, where they stayed a week to build a church. Within 2 weeks of returning home, 27 of the travelers complained of flu-like symptoms and testing revealed exposure to the fungus that causes CM. The disease is also known by a number of other names including desert fever, Posadas disease, San Joaquin fever, San Joaquin Valley disease, San Joaquin Valley fever, and valley fever. How to pronounce, definition of, audio dictionary, medical dictionary
Views: 88 Medical Dictionary